Wells Syndrome – An Odyssey

  • Birgit Heinig Center of Physical and Rehabilitative Medicine, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany
  • Aleksandra Vojvodic Military Medical Academy of Belgrade, Belgrade, Serbia
  • Torello Lotti Department of Dermatology, University of Rome “G. Marconi”, Rome, Italy
  • Michael Tirant Department of Dermatology, University of Rome “G. Marconi”, Rome, Italy
  • Uwe Wollina Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany
Keywords: Eosinophilic skin diseases, Wells syndrome, Flame figure, Eosinophila, Treatment, Interleukin-5


BACKGROUND: Wells syndrome is a rare idiopathic dermatosis of the eosinophilic spectrum. Diagnostic criteria include cutaneous eruptions of variable morphology with eosinophilic infiltrates, peripheral blood eosinophilia, a relapsing, remitting course, and exclusion of systemic disease. Diagnosis is often delayed.

CASE PRESENTATION: We present a 28-year older man with recently developed pruritic and sometimes painful erythema. His medical history was positive for coughing in the evening that started in November 2012. Later, a pansinusitis developed. Early diagnosis improves the outcome.

CONCLUSION: Standardized treatment has yet to be developed. In our case, systemic corticosteroids were of limited value only.


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How to Cite
Heinig B, Vojvodic A, Lotti T, Tirant M, Wollina U. Wells Syndrome – An Odyssey. Open Access Maced J Med Sci [Internet]. 2019Jun.30 [cited 2020Oct.26];7(18):3002-5. Available from: https://www.id-press.eu/mjms/article/view/oamjms.2019.572

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