Rosacea Flare - Up after Photodynamic Therapy (PDT) for Field Cancerization and a Review on Adverse Events with PDT in General

  • Uwe Wollina Academic Teaching Hospital DresdenDepartment of Dermatology and Allergology
  • Alena Bitel Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital
  • Aleksandra Vojvodic Military Medical Academy of Belgrade, Serbia, and University of Rome Guglielmo Marconi Rome, Italy
  • Torello Lotti Department of Dermatology, University of Rome “G. Marconi”, Rome, Italy
Keywords: Actinic keratosis, Field cancerization, Photodynamic therapy, Adverse events, Pain, Rosacea

Abstract

BACKGROUND: Actinic keratoses (AKs) are precancerous epidermal lesions induced by chronic exposure to ultraviolet light. Several topical and surgical treatments are available. For field cancerization, photodynamic therapy (PDT) is a very effective noninvasive treatment with excellent outcome and cosmesis. The management of treatment-associated adverse events, however, is crucial to achieve the treatment aims and to ensure patients adherence to PDT.

CASE REPORT: We report on adverse events and their management related to PDT. We conducted literature research on PUBMED (R). Also, we present a case of an uncommon adverse event-PDT-induced rosacea flare-up on scalp and eyes. The patient was treated successfully by submicrobial slow-release doxycycline orally.

Conclusions: PDT is an excellent treatment option for multiple AKs such as in bald scalp field cancerization. The management of adverse events during and after PDT is an essential part of a successful treatment plan.

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Author Biographies

Uwe Wollina, Academic Teaching Hospital DresdenDepartment of Dermatology and Allergology

Head of Department of Dermatology and Allergology

Alena Bitel, Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital

Assistant

Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital

Aleksandra Vojvodic, Military Medical Academy of Belgrade, Serbia, and University of Rome Guglielmo Marconi Rome, Italy

Professor of Dermatology

Military Medical Academy of Belgrade, Serbia, and University of Rome Guglielmo Marconi Rome, Italy

Torello Lotti, Department of Dermatology, University of Rome “G. Marconi”, Rome, Italy

Professor of Dermatology

 

Department of Dermatology, University of Rome “G. Marconiâ€, Rome, Italy

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Published
2019-08-20
How to Cite
1.
Wollina U, Bitel A, Vojvodic A, Lotti T. Rosacea Flare - Up after Photodynamic Therapy (PDT) for Field Cancerization and a Review on Adverse Events with PDT in General. Open Access Maced J Med Sci [Internet]. 2019Aug.20 [cited 2020Oct.20];7(18):2998-001. Available from: https://www.id-press.eu/mjms/article/view/oamjms.2019.536

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