Treatment of Psoriasis: Novel Approaches to Topical Delivery

  • Uwe Wollina Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany
  • Michael Tirant Department of Dermatology, University of Rome “G. Marconi”, Rome, Italy
  • Aleksandra Vojvodic Military Medical Academy of Belgrade, Belgrade, Serbia
  • Torello Lotti Department of Dermatology, University of Rome “G. Marconi”, Rome, Italy
Keywords: Topical drug therapy, Psoriasis, Nanoparticles, Laser-assisted drug delivery, Foams, Niosomes, Ethosomes


Topical treatment is the cornerstone for the management of mild to moderate psoriasis. Despite efforts in drug development, patient's satisfaction with the available topical treatments is limited. A strategy to improve safety, efficacy and comfort of topical treatment provides the development of new drug delivery and drug carrier systems. This review provides an overview of recent advances in this field with a focus on psoriasis. Laser-assisted drug delivery, foam formulations, nanoparticles, ethosomes, and niomes are considered. Hopefully, these new developments will improve topical drug therapy and patient satisfaction.


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How to Cite
Wollina U, Tirant M, Vojvodic A, Lotti T. Treatment of Psoriasis: Novel Approaches to Topical Delivery. Open Access Maced J Med Sci [Internet]. 2019Aug.30 [cited 2021Jan.24];7(18):3018-25. Available from:

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