Systematic Evaluation of Efficacy and Safety of Acupuncture Treatment for Patients with Atrial Fibrillation

  • Yu Fei Department of Cardiology, the Second Hospital, Jilin University, Changchun, Jilin 130041, China
  • Rui Fei Department of Cell Biology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, China
  • Jing Zhang Department of Cardiology, the Second Hospital, Jilin University, Changchun, Jilin 130041, China
  • Yaoyao Sun Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China
  • Qiong Yu Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China
Keywords: Atrial Fibrillation, Acupuncture, Meta-analysis

Abstract

BACKGROUND: Atrial fibrillation (AF) is one of the most common types of arrhythmia diagnosed in clinical practice. Due to its negative effects on people's physical and mental health, it is necessary to prevent and treat AF. Recently, scholars have found that acupuncture can be used to treat AF, but some scholars have questioned its therapeutic efficacy.

AIM: Therefore, this study was performed to assess the efficacy and safety of acupuncture treatment for AF patients.

METHODS: Previously published research articles were retrieved from six databases, and the data was analysed using RevMan5.3 software with a statistically significant difference defined as P < 0.05.

RESULTS: A total of 8 relevant kinds of literature were retrieved containing 633 AF patients (323 in the treatment group and 310 in the control group). Acupuncture treatment increased the total efficacy and the rate of AF cardioversion to sinus rhythm (RR: 1.38; 95% CI: 1.25 to 1.53 vs RR: 1.40;95% CI: 1.16 to 1.69; each P < 0.05), and decreased the time of AF cardioversion to sinus rhythm, the heart rate and incidence of adverse effects (RR: -3.95; 95% CI: -4.98 to -2.91 vs RR: -14.54; 95% CI: -24.09 to -5.00 vs RR: 0.48; 95% CI: 0.21 to 1.11, each P < 0.05). There was difference between retention time more and less than 30 minutes (I2 = 74.9%, P = 0.05). The funnel plot displayed a symmetrical and funnel-form shape, indicating low bias.

CONCLUSION: Acupuncture has a good therapeutic effect and safety profile on patients with AF, and its application in clinical practice should be considered.

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References

Chugh SS, Havmoeller R, Narayanan K, Singh D, Rienstra M, et al. Worldwide epidemiology of atrial fibrillation: a global burden of disease 2010 study. Circulation. 2014; 129(8):837-47. https://doi.org/10.1161/CIRCULATIONAHA.113.005119 PMid:24345399 PMCid:PMC4151302

Ma CS. Epidemiology of atrial fibrillation. Med Philosophy. 2016; 37(11): 8-26.

Khaji A, Kowey PR. Update on atrial fibrillation. Trends Cardiovasc Med. 2017; 27(1):14-25. https://doi.org/10.1016/j.tcm.2016.06.007 PMid:27520496

Pellman J, Sheikh F. Atrial fibrillation: mechanisms, therapeutics, and future directions. Compr Physiol. 2015; 5(2):649-65. https://doi.org/10.1002/cphy.c140047 PMid:25880508 PMCid:PMC5240842

Falk RH. Rate control is preferable to rhythm control in the majority of patients with atrial fibrillation. Circulation. 2005; 111(23):3141-50. https://doi.org/10.1161/CIRCULATIONAHA.104.485565 PMid:15956148

Guo XY, Ma CS. Atrial fibrillation therapy: present and future. Clin Focus. 2016; 31(1):7-9.

Lombardi F., Belletti S, Battezzati PM, Lomuscio A. Acupuncture for paroxysmal and persistent atrial fibrillation: an effective non-pharmacological tool? World Journal of Cardiology. 2012; 4(3):60-5. https://doi.org/10.4330/wjc.v4.i3.60 PMid:22451853 PMCid:PMC3312232

Wu RD, Lin LF. Clinical observation on wrist-ankle acupuncture for treatment of paroxysmal supraventricular tachycardia. Zhongguo Zhen Jiu. 2006; 26:854-56.

Lau EW, Birnie DH, Lemery R, Tang AS, Green MS. Acupuncture triggering inappropriate ICD shocks. Europace. 2005; 7(1):85-6. https://doi.org/10.1016/j.eupc.2004.05.010 PMid:15670973

Xu HK, Zhang YF. Comparison between therapeutic effects of acupuncture and intravenous injection of amiodarone in the treatment of paroxysmal atrial fibrillation and atrial flutter. Zhongguo Zhen Jiu. 2007; 27(2):96-8.

Lomuscio A, Belletti S, Battezzati PM, Lombardi F. Efficacy of acupuncture in preventing atrial fibrillation recurrences after electrical cardioversion. J Cardiovasc Electrophysiol. 2011; 22(3):241-7. https://doi.org/10.1111/j.1540-8167.2010.01878.x PMid:20807278

Han BD. Clinical observation of 62 cases of paroxysmal rapid atrial fibrillation treated with acupuncture and drugs. JETCM. 2012; 21(2):303.

Zhang XL, Lou M, Wang HY. Clinical efficacy observation on paroxysmal atrial fibrillation treated by acupuncture combined with Wenxin granule. Zhongguo Zhen Jiu. 2013; 33(8):686-8.

Xia YS, Ge F, Qiu XH.50 cases of paroxysmal rapid atrial fibrillation were treated with acupuncture. Chin Med Modern distance edu. 2014; 12(8):83.

Yan YH, Li BX, Wu LY. Clinical observation of paroxysmal atrial fibrillation treated with a combination of acupuncture and medicine. Zhejiang J of Tradit Chin Med. 2014; 49(11):833.

Xu BZ. Clinical value of acupuncture combined with Wenxin Granule in the treatment of paroxysmal atrial fibrillation. Med Recapitulate. 2015; 21(17):3239-41.

Park J, Kim HS, Lee SM, Yoon K, Kim WS, et al. Acupuncture antiarrhythmic effects on drug refractory persistent atrial fibrillation: study protocol for a randomised, controlled trial. Evid Based Complement Alternat Med. 2015; 2015:613970. https://doi.org/10.1155/2015/613970 PMid:25784948 PMCid:PMC4346697

Ming Liu. Systematic review, meta-analysis, design and implementation method, first edition. Beijing: People's Medical Publishing House, 2011:p69.

Van Wormer AM, Lindquist R, Sendelbach SE. The effects of acupuncture on cardiac arrhythmias: a literature review. Heart Lung. 2008; 37(6):425-31. https://doi.org/10.1016/j.hrtlng.2007.11.002 PMid:18992625

Dilber D, Čerkez-Habek J, Barić H, Gradišer M. Atrial fibrillation cardioversion following acupuncture. Saudi Med J. 2015; 36(11):1351-3. https://doi.org/10.15537/smj.2015.11.12891 PMid:26593171 PMCid:PMC4673375

Liu J, Yao HF. Clinical research progress of traditional Chinese medicine in treating atrial fibrillation. Clin J Tradit Chin Med. 2017; 29(7):1123-1124.

Cha R, Yoon D, Kim J, Lee M, Lee GL A study of Sa-Ahm's thoughts on the four-needle acupuncture technique with the five-element theory. J Acupunct Meridian Stud. 2014; 7(5):265-73. https://doi.org/10.1016/j.jams.2014.06.002 PMid:25441953

Kanmanthareddy A, Reddy M, Ponnaganti G, Sanjani HP, Koripalli S, et al. Alternative medicine in atrial fibrillation treatment -Yoga, acupuncture, biofeedback and more. J Thorac Dis. 2015; 7(2):185-92. PMid:25713735 PMCid:PMC4321072

Wang Y, Wang W, Li D, Li J, Dai J, et al. The beneficial effect of electro-acupuncture given at PC6 (Neiguan-point) by the increase in cardiac transient outward K+ current channel which depends on the gene and protein expressions in artificially induced myocardial ischemia rats. Acupunct Electrother Res. 2014; 39(3-4):259-73. https://doi.org/10.3727/036012914X14109544776132 PMid:25693308

Xiao Y, Le W, Huang H, Zhou L, Tian JY, et al. Effect of electroacupuncture of "Fenglong" (ST 40) on levels of blood lipid and macrophage TNF-alpha and IL-6 in hyperlipidemic rats. Zhen Ci Yan Jiu. 2013; 38(6):459-64. PMid:24579360

Kurono Y, Minagawa M, Ishigami T, Yamada A, Kakamu T, et al. Acupuncture to Danzhong but not to Zhongting increases the cardiac vagal component of heart rate variability. Auton Neurosci. 2011; 161(1-2):116-20. https://doi.org/10.1016/j.autneu.2010.12.003 PMid:21216208

Yi YH, Zhu YH, Pan ZB, Wang D, Zou TT, Chen XY. Brief analysis on the influence of needle retaining time on acupuncture effects. Shanghai J Tradit Chin Med. 2017; 51(1):37-39.

Li CJ, Yang GN, Gong WJ. Real-time effect of retaining needle at Lingtai (GV 10) and Shendao (GV 11) on ST-T segment on cardiogram of angina pectoris of coronary heart disease. Shanghai J Acu-mox. 2016; 35(1):27-29.

Lin YF. Analysis of influencing factors of acupuncture effect. Asia-pacific Tradit Med. 2016; 12(15):100-102.

Chen LG, Cai XH. Discussion on the Significance and Time of Needle Retention. Zhongguo Zhen Jiu. 1996; 16(6):40-42.

Published
2019-01-26
How to Cite
1.
Fei Y, Fei R, Zhang J, Sun Y, Yu Q. Systematic Evaluation of Efficacy and Safety of Acupuncture Treatment for Patients with Atrial Fibrillation. Open Access Maced J Med Sci [Internet]. 2019Jan.26 [cited 2021Jan.24];7(3):461-6. Available from: https://www.id-press.eu/mjms/article/view/oamjms.2019.036
Section
F - Review Articles

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