Risk Factors Associated with Neonatal Jaundice: A Cross-Sectional Study from Iran

  • Sayed Yousef Mojtahedi Department of Pediatrics, Ziyaeian Hospital, Tehran University of Medical Sciences, Tehran
  • Anahita Izadi Department of Pediatric Infection Disease, Tehran University of Medical Science, Tehran
  • Golnar Seirafi School of Medicine, Ziyaeian Hospital, Tehran University of Medical Sciences, Tehran
  • Leila Khedmat Department of Community Medicine, School of Medicine,Tehran University of Medical Science, Tehran, Iran; 5Health Management Research Center and Department of Community Medicine, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran
  • Reza Tavakolizadeh Department of Pediatrics, Tehran University of Medical Sciences, Tehran
Keywords: Neonatal Jaundice, Predisposing factors, Jaundice


BACKGROUND: Neonatal jaundice is one of the main causes of the patient's admission in the neonatal period and is potentially linked to morbidity.

AIM: This study aimed to determine the possible risk factors for neonatal jaundice.

METHODS: We investigated the case of infants who were admitted to the neonatal department of Ziyaeian hospital and Imam Khomeini Hospital for jaundice. Simple random sampling was used to evaluate variables related to maternal and neonatal predisposing factors based on the medical records and clinical profiles. All variables in this study were analysed using SPSS software.

RESULTS: In this study, about 200 mothers and neonates were examined. Our findings depicted that mother's WBC, Hb, PLT, and gestational age were associated with jaundice (P < 0.05). Furthermore, there were significant relationships between different degrees of bilirubin with TSH, T4 levels and G6PD (P < 0.05). In fact, TSH, T4 levels and G6PD were found to be linked to neonatal hyperbilirubinemia. The risk factors for jaundice in our study population comprise some predisposing factors such as WBC, Hb, PLT, gestational age, TSH, and T4 levels, as well as G6PD. Neonates at risk of jaundice are linked to some maternal and neonatal factors that can provide necessary interventions to reduce the burden of the disease. Therefore, identification of associated factors can facilitate early diagnosis, and reduce subsequent complications.

CONCLUSION: Neonatal jaundice should be considered as the main policy in all health care settings of the country. Therefore, identification of factors affecting the incidence of jaundice can be effective in preventing susceptible predisposing factors in newborns and high-risk mothers.


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How to Cite
Mojtahedi SY, Izadi A, Seirafi G, Khedmat L, Tavakolizadeh R. Risk Factors Associated with Neonatal Jaundice: A Cross-Sectional Study from Iran. Open Access Maced J Med Sci [Internet]. 2018Aug.11 [cited 2020Nov.26];6(8):1387-93. Available from: https://www.id-press.eu/mjms/article/view/oamjms.2018.319
B - Clinical Sciences