In Vivo Comparative Evaluation of Periapical Healing in Response to a Calcium Silicate and Calcium Hydroxide Based Endodontic Sealers

  • Dalia Y. Zaki Restorative and Dental Materials Department, National Research Centre (NRC), El Bohouth St., 12622 Dokki, Giza
  • Mohamed H. Zaazou Restorative and Dental Materials Department, National Research Centre (NRC), El Bohouth St., 12622 Dokki, Giza http://orcid.org/0000-0003-3678-1323
  • Maram E. Khallaf Restorative and Dental Materials Department, National Research Centre (NRC), El Bohouth St., 12622 Dokki, Giza
  • Tamer M. Hamdy Restorative and Dental Materials Department, National Research Centre (NRC), El Bohouth St., 12622 Dokki, Giza http://orcid.org/0000-0003-0948-194X
Keywords: Bioceramic sealer, Calcium hydroxide, Root canal sealer

Abstract

BACKGROUND: The composition of the root canal filling materials together with the apical limit of the root canal obturation affect the complete periapical healing after root canal therapy.

AIM: This study was performed to evaluate and compare the periapical healing in response to calcium-silicate (iRoot SP) and calcium-hydroxide (Apexit) based-sealers.

MATERIAL AND METHODS: Seventy-two upper premolars root canals of six dogs were used. The teeth were randomly assigned to four groups: Group one: roots were obturated using gutta-percha and Apexit-sealer; Group two: roots were obturated using gutta-percha&iRoot SP-sealer; Group three: the teeth were left open without obturation; Group four: where healthy teeth were used as a negative control. Teeth were evaluated after one, two and three months. The newly formed mineralised apical tissue and the periapical inflammatory infiltrate of the obtained photomicrographs were evaluated, and scorings were statistically-analysed.

RESULTS: The mean percentage of the periapical inflammatory infiltrates and mineralisation scoring after one, two and three months evaluation period were not significantly different among the four groups (P > 0.05).

CONCLUSIONS: Regardless of the sealer used, iRoot SP and Apexit promote healing of periapical tissues. IRoot SP sealer showed early insignificant more partial and almost full healing after two and three months.

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References

Wu MK, Tigos E, Wesselink PR. An l8-month longitudinal study on a new silicon-based sealer, RSA RoekoSeal: A leakage study in vitro. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2002; 94(4):499-502. https://doi.org/10.1067/moe.2002.124859

Schäfer E, Zandbiglari T. Solubility of rootâ€canal sealers in water and artificial saliva. International endodontic journal. 2003; 36(10):660-9. https://doi.org/10.1046/j.1365-2591.2003.00705.x PMid:14511222

Leonardo MR, Utrilla LS, Assed S, Ether SS. Calcium hydroxide root canal Sealers—Histopathologic evaluation of apical and peripaical repair after endodontic treatment. Journal of endodontics. 1997; 23(7):428-32. https://doi.org/10.1016/S0099-2399(97)80296-8

Al-Awadhi S, Spears R, Gutmann JL, Opperman LA. Cultured primary osteoblast viability and apoptosis in the presence of root canal sealers. J Endod. 2004; 30:527–33. https://doi.org/10.1097/00004770-200407000-00016 PMid:15220652

Al-Haddad A, Ab Aziz C, Zeti A. Bioceramic-based root canal sealers: a review. International journal of biomaterials. 2016; 2016.

Tanomaru Filho M, Leonardo MR, Silva LA, Utrilla LS. Effect of different root canal sealers on periapical repair of teeth with chronic periradicular periodontitis. Int Endod J. 1998; 31:85–9. https://doi.org/10.1046/j.1365-2591.1998.00134.x PMid:9868933

Leonardo MR, Almeida WA, Da Silva LA, Utrilla LS. Histological evaluation of the response of apical tissues to glass ionomer and zinc oxideâ€eugenol based sealers in dog teeth after root canal treatment. Dental Traumatology. 1998; 14(6):257-61. https://doi.org/10.1111/j.1600-9657.1998.tb00849.x

Zhang H, Shen Y, Ruse ND, Haapasalo M. Antibacterial activity of endodontic sealers by modified direct contact test against Enterococcus faecalis. Journal of endodontics. 2009; 35(7):1051-5. https://doi.org/10.1016/j.joen.2009.04.022 PMid:19567333

Koch K, Brave D. Bioceramic technology-the game changer in endodontics. Endodontic Practice US. 2009; 12:7-11.

Huang F-M, Tai K-W, Chou M-Y, Chang Y-C. Cytotoxicity of resin-, zinc oxide–eugenol-, and calcium hydroxide-based root canal sealers on human periodontal ligament cells and permanent V79 cells. Int Endod J. 2002; 35:153–8. https://doi.org/10.1046/j.1365-2591.2002.00459.x

de Paula-Silva FW, Júnior MS, Leonardo MR, Consolaro A, da Silva LA. Cone-beam computerized tomographic, radiographic, and histologic evaluation of periapical repair in dogs' post-endodontic treatment. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2009; 108(5):796-805. https://doi.org/10.1016/j.tripleo.2009.06.016 PMid:19734073

Brasil DS, Soares JA, Horta MC, Ferreira CL, Nunes E, Chaves GG, Silveira FF. Periapical repair in dog teeth: root canal adhesive filling by using the Resilon system. Journal of endodontics. 2010; 36(3):482-8. https://doi.org/10.1016/j.joen.2009.11.020 PMid:20171367

Holland R, Otoboni-Filho JA, Souza V, Nery MJ, Bernabé PF , Dezan E Jr. A comparison of one versus two appointment endodontic therapy in dogs' teeth with apical periodontitis. J Endod. 2003; 29:121-4. https://doi.org/10.1097/00004770-200302000-00009 PMid:12597712

Holland R, Sant'anna Júnior A, Souza VD, Dezan Junior E, Otoboni Filho JA, Bernabé PF, Nery MJ, Murata SS. Influence of apical patency and filling material on healing process of dogs' teeth with vital pulp after root canal therapy. Brazilian dental journal. 2005; 16(1):9-16. https://doi.org/10.1590/S0103-64402005000100002 PMid:16113927

Leonardo MR, Flores DS, de Toledo Leonardo R, da Silva LA. A comparison study of periapical repair in dogs' teeth using RoekoSeal and AH plus root canal sealers: a histopathological evaluation. Journal of endodontics. 2008; 34(7):822-5. https://doi.org/10.1016/j.joen.2008.03.029 PMid:18570987

Peters OA, Peters CI. Cleaning and shaping of the root canal system. Pathways of the Pulp. 2006; 9:290-357.

de Vasconcelos BC, Bernardes RA, Luna Cruz SM, Húngaro Duarte MA, de Magalhães Padilha P, Bernardineli N, Garcia RB, Bramante CM, de Moraes IG. Ceará, Brazil Evaluation of pH and calcium ion release of new root-end filling materials. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009; 108:135-9. https://doi.org/10.1016/j.tripleo.2009.02.026 PMid:19451009

Mohammadi Z, Dummer P.M.H., Properties and applications of calcium hydroxide in endodontics and dental traumatology, Int Endod J. 2011; 44:697-730. https://doi.org/10.1111/j.1365-2591.2011.01886.x PMid:21535021

Zhang W, Li Z, and Peng B. Assessment of a new root canal sealer's apical sealing ability. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics. 2009; 107:e79–e82. https://doi.org/10.1016/j.tripleo.2009.02.024 PMid:19464650

Zhu X, Yuan Z, Yan P, Li Y, Jiang H, Huang S. Effect of iRoot SP and mineral trioxide aggregate (MTA) on the viability and polarization of macrophages. Arch Oral Biol. 2017; 80:27–33. https://doi.org/10.1016/j.archoralbio.2017.03.010 PMid:28364673

Desai S, Chandler N. Calcium hydroxide–based root canal sealers: a review. Journal of endodontics. 2009; 35(4):475-80. https://doi.org/10.1016/j.joen.2008.11.026 PMid:19345790

Kumaravadivel MS, Pradeep S. Recent advancements of endodontic sealers-a review. International Journal of Pharmacy and Technology. 2016; 8:4060–75.

Dudeja C, Taneja S, Kumari M, Singh N. An in vitro comparison of effect on fracture strength, pH and calcium ion diffusion from various biomimetic materials when used for repair of simulated root resorption defects. Journal of conservative dentistry: JCD. 2015; 18(4):279. https://doi.org/10.4103/0972-0707.159720 PMid:26180410 PMCid:PMC4502121

Published
2018-08-15
How to Cite
1.
Zaki DY, Zaazou MH, Khallaf ME, Hamdy TM. In Vivo Comparative Evaluation of Periapical Healing in Response to a Calcium Silicate and Calcium Hydroxide Based Endodontic Sealers. Open Access Maced J Med Sci [Internet]. 2018Aug.15 [cited 2020Nov.29];6(8):1475-9. Available from: https://www.id-press.eu/mjms/article/view/oamjms.2018.293
Section
D - Dental Sciences