Early Versus Delayed Umbilical Cord Clamping on Physiologic Anemia of the Term Newborn Infant

  • Fatma Alzaree National Research Center, Child Health Department, Eltahrir Street, Dokki, Guiza, Cairo 1234
  • Ahmed Elbohoty Ain Shams University Faculty of Medicine, Cairo
  • Mohamed Abdellatif Ain Shams University Faculty of Medicine, Cairo
Keywords: Delayed cord clamping, Umbilical cord milking, Neonatal physiologic anaemia, Term newborn


AIM: Our study aims to make a comparison between the effects of milking of umbilical cord versus delayed cord clamping on Hemoglobin level at 6 weeks from delivery among term neonates and which method is more beneficial for them.

DESIGN: It was a randomised control study. Participants were randomised into 2 groups; Group 1: 125 women were assigned to delay cord clamping; Group 2: 125 women were assigned to milking of the umbilical cord 5 times before cutting. Student t-test was used to compare between the two groups for quantitative data, for qualitative data chi-square test and the Correlation coefficient was done to test the association between variables.

SETTING: This study was at El-Galaa Teaching Hospital, labour suite. Cairo, Egypt.

PARTICIPANTS: A group of 250 pregnant women starting from ≥ 37 weeks’ gestational age.

INTERVENTION: In this study, we searched if the mechanism of milking or delayed cord clamping could give some of the positive benefits for neonates or not.

RESULTS: In this study, we found that milking of the umbilical cord five times as in group 1 was associated with higher hemoglobin levels at 6 weeks after birth, at physiological anemia of the fetus and significant but clinically there was no difference between the two groups (10.4 ± 0.5 and 10.6 ± 0.5 respectively, P < 0.001). Also, there was a positive correlation between haemoglobin of the mother and the newborn during the first day and after 6 weeks with r = 0.349 and 0.283 respectively and a P value < 0.001. Furthermore, there was a positive correlation between the haemoglobin of the fetus after the first day and fetus at 6 weeks with r = 0.534 and a P value < 0.001. For most other outcomes (including APGAR score, positive pressure ventilation, poor neonatal outcomes such as respiratory distress syndrome there were no significant differences between the two groups. Our study may recommend the use of umbilical cord milking in term babies when delayed cord clamping is unavailable.

CONCLUSION: Umbilical cord blood milking after its clamping improves some important haematological parameters for newborns, especially in countries with high incidence of anaemia in newborns and children.


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How to Cite
Alzaree F, Elbohoty A, Abdellatif M. Early Versus Delayed Umbilical Cord Clamping on Physiologic Anemia of the Term Newborn Infant. Open Access Maced J Med Sci [Internet]. 2018Aug.15 [cited 2020Nov.29];6(8):1399-404. Available from: https://www.id-press.eu/mjms/article/view/oamjms.2018.286
B - Clinical Sciences