Total Antioxidant Capacity, Haematological and Coagulation Parameters after Orthodox Christian Fast
BACKGROUND: Orthodox Christian believers fast abstaining from meat, eggs, dairy products or even fish and oil in certain days of the fasting period, three times a year.
AIM: The present study aimed to investigate the impact of a 48-day fast before Easter in blood count parameters, coagulation and antioxidant status.
MATERIAL AND METHODS: A total of 35 healthy volunteers, 19-66 years old, were included in the study. White blood cells (WBC), lymphocytes (Lymph), granulocytes (Gran), haemoglobin (Hb), hematocrit (Ht), red blood cells (RBC), mean erythrocyte volume (MCV), platelets (Plt), were measured. Blood coagulation parameters, such as PT, aPTT, fibrinogen concentration, factor VII activity were also determined, and INR (PTsample/PTcontrol) and aPTT ratio (aPTTsample/aPTTcontrol) were calculated. Total antioxidant capacity (TAC) was assayed.
RESULTS: Levels of all parameters remained within normal. By the end of the fasting period, lymphocytes and TAC levels were significantly increased (p = 0.011), whereas all the other parameters, except fibrinogen, were significantly decreased.CONCLUSION: Orthodox Christian fast impairs all haematological and coagulation parameters and seems to be beneficial in the body antioxidant protection.
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Trepanowski JF, Bloomer RJ. The impact of religious fasting on human health. Nutr J. 2010; 9:57. https://doi.org/10.1186/1475-2891-9-57 PMid:21092212 PMCid:PMC2995774
Pieters M, de Maat MP. Diet and haemostasis â€” A comprehensive overview Blood Rev. 2015; 29(4):231-41. https://doi.org/10.1016/j.blre.2014.12.005 PMid:25555324
Vorster HH, Cummings JH, Jerling JC. Diet and haemostatic processes. Nutr Res Rev. 1997; 10(1):115-35. https://doi.org/10.1079/NRR19970007 PMid:19094260
Perez-Jimenez F, Delgado Lista J, Perez-MartÄ±nez P, et al. Olive oil and haemostasis: a review on its healthy effects. Public Health Nutr. 2006; 9(8A):1083-8. https://doi.org/10.1017/S1368980007668566 PMid:17378945
Zamora-Ros R, Serafini M, Estruch R, et al.; PREDIMED Study Investigators. Mediterranean diet and non-enzymatic antioxidant capacity in the PREDIMED study: evidence for a mechanism of antioxidant tuning. Nutr Metab Cardiovasc Dis. 2013; 23(12):1167-74. https://doi.org/10.1016/j.numecd.2012.12.008 PMid:23484910
Kolomvotsou AI, Rallidis LS, Mountzouris KC, et al. Adherence to Mediterranean diet and close dietetic supervision increase total dietary antioxidant intake and plasma antioxidant capacity in subjects with abdominal obesity. Eur J Nutr. 2013; 52(1):37- 48. https://doi.org/10.1007/s00394-011-0283-3 PMid:22237557
Ortner HM, Vitali ÄŒD, RaheliÄ‡ D, BoÅ¾ikov V. The Effect of the Mediterranean Diet on Serum Total Antioxidant Capacity in Obese Patients: A Randomized Controlled Trial. J Am Coll Nutr. 2016; 35(3):224-35. https://doi.org/10.1080/07315724.2014.982770 PMid:25989426
Liali M, Printz's L, Vagdatli E, Pantziarela E, Konstantinidou V, Limperaki E, et al. The Effects of Orthodox Christian Fasting on Blood Coagulation. IJBLS. 2015; 4(2):39-43.
Allman-Farinelli MA, Gomes K, Favaloro EJ, Petocz P. A diet rich in high-oleic-acid sunflower oil favorably alters low-density lipoprotein cholesterol, triglycerides, and factor VII coagulant activity. J Am Diet Assoc. 2005;105(7):1071-9. https://doi.org/10.1016/j.jada.2005.04.008 PMid:15983523
McEwen BJ. The influence of diet and nutrients on platelet function. Semin Thromb Hemost. 2014; 40(2):214-26. https://doi.org/10.1055/s-0034-1365839 PMid:24497119
Latifynia A, Vojgani M, Gharagozlou MJ, Sharifian R. Neutrophil function (innate immunity. J Ayub Med Coll Abbottabad. 2009; 21(4):111-5. PMid:21067041
Sarri KO, Kafatos GA, Higgins S. Is religious fasting related to iron status in Greek Orthodox Christians? Br J Nutr. 2005; 94:198â€“203. https://doi.org/10.1079/BJN20051472 PMid:16115353
GonÃ§alves S, Moreira E, Grosso C, Andrade PB, ValentÃ£o P, Romano A. Phenolic profile, antioxidant activity and enzyme inhibitory activities of extracts from aromatic plants used in Mediterranean diet. J Food Sci Technol. 2017; 54(1):219-227. https://doi.org/10.1007/s13197-016-2453-z PMid:28242919 PMCid:PMC5305718
Sarri KO, Tzanakis NE, Linardakis MK, Mamalakis GD, Kafatos AG. Effects of Greek Orthodox Christian Church fasting on serum lipids and obesity. BMC Public Health. 2003; 3:16. https://doi.org/10.1186/1471-2458-3-16 PMid:12753698 PMCid:PMC156653
Sarri KO, Linardakis MK, Bervanaki FN, Tzanakis NE, Kafatos AG. Greek Orthodox fasting rituals: a hidden characteristic of the Mediterranean diet of Crete. Br J Nutr. 2004; 92(2):277-84. https://doi.org/10.1079/BJN20041197 PMid:15333159
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