Intralesional Diode Laser 1064 nm for the Treatment of Hidradenitis Suppurativa: A Report of Twenty Patients

  • Gabriella Fabbrocini University of Naples "Federico II" - Department of Clinical Medicine and Surgery, Section of Dermatology, Napoli
  • Katlein França University of Miami School of Medicine, 1400 NW 10th Avenue, Miami, Florida 33136-1015
  • Torello Lotti University of Rome "G. Marconi" - Centro Studi per la Ricerca Multidisciplinare e Rigenerativa (CSRMR), Rome
  • Claudio Marasca University of Naples "Federico II" - Department of Clinical Medicine and Surgery, Section of Dermatology, Napoli
  • Maria Carmela Annunziata University of Naples "Federico II" - Department of Clinical Medicine and Surgery, Section of Dermatology, Napoli
  • Sara Cacciapuoti University of Naples "Federico II" - Department of Clinical Medicine and Surgery, Section of Dermatology, Napoli
  • Anna Masarà University of Naples "Federico II" - Department of Clinical Medicine and Surgery, Section of Dermatology, Napoli
  • Marco Romanelli University of Pisa - Department of Dermatology, Pisa
  • Jacopo Lotti University of Rome "G. Marconi" - Department of Nuclear, Subnuclear and Radiation Physics, Rome
  • Uwe Wollina Städtisches Klinikum Dresden, Department of Dermatology and Allergology, 01067 Dresden
  • Georgi Tchernev Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior (MVR-Sofia), General Skobelev 79, 1606 Sofia; Onkoderma - Policlinic for Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606, Sofia
  • Nicola Zerbinati Universita degli Studi dell'Insubria Dipartimento di Scienze Chirurgiche e Morfologiche, Varese
Keywords: diode laser, 1064 nm, hidradenitis suppurativa, human treatment, chronic inflammatory disease

Abstract

AIM: Hidradenitis suppurativa (HS) is a chronic inflammatory disease, commonly characterized by painful, deep dermal abscesses and chronic draining sinus tracts. Recently, laser and light-based therapies have become more commonly used in the management of HS.

MATERIAL AND METHODS: We report 20 HS patients treated with a 1064 nm wavelength, emitted from a diode laser, launched in an optical fibre through intracavitary modalities.

RESULTS: Each patient underwent four laser sessions, one every two weeks. we recorded a significative reduction (31%) of Sartorius score from 28.55 ± 13.04 to 19.75 ± 12.29 after 4 laser sessions (p < 0.05). No one has had a worsening of the disease.

CONCLUSION: Intralesional diode laser 1064 nm can be a good treatment option for patients with moderate and localized hidradenitis suppurativa, because it is minimally invasive, doesn’t have significant complications and provides a rapid post-treatment recovery.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

References

Naik HB. Hidradenitis suppurativa, introduction. Semin Cutan Med Surg. 2017; 36(2):41. https://doi.org/10.12788/j.sder.2017.025 PMid:28538741

Hoffman LK, Ghias MH, Garg A, Hamzavi IH, Alavi A, Lowes MA. Major gaps in understanding and treatment of hidradenitis suppurativa. Semin Cutan Med Surg. 2017 Jun;36(2):86-92. https://doi.org/10.12788/j.sder.2017.024 PMid:28538750

Kimball AB, Kerdel F, Adams D, Mrowietz U, Gelfand JM, Gniadecki R, Prens EP, Schlessinger J, Zouboulis CC, van der Zee HH, Rosenfeld M, Mulani P, Gu Y, Paulson S, Okun M, Jemec GB. Adalimumab for the treatment of moderate to severe Hidradenitis suppurativa: a parallel randomized trial. Ann Intern Med. 2012; 157(12):846-55. https://doi.org/10.7326/0003-4819-157-12-201212180-00004 PMid:23247938

Kimball AB, Sobell JM, Zouboulis CC, Gu Y, Williams DA, Sundaram M, Teixeira HD, Jemec GB. HiSCR (Hidradenitis Suppurativa Clinical Response): a novel clinical endpoint to evaluate therapeutic outcomes in patients with hidradenitis suppurativa from the placeboâ€controlled portion of a phase 2 adalimumab study. Journal of the European Academy of Dermatology and Venereology. 2016; 30(6):989-94. https://doi.org/10.1111/jdv.13216 PMid:26201313 PMCid:PMC5034809

Orenstein LA, Micheletti RG. Medical management of hidradenitis suppurativa. Semin Cutan Med Surg. 2017; 36(2):62-66. https://doi.org/10.12788/j.sder.2017.021 PMid:28538746

Scuderi N, Monfrecola A, Dessy LA, Fabbrocini G, Megna M, Monfrecola G. Medical and Surgical Treatment of Hidradenitis Suppurativa: A Review. Skin Appendage Disord. 2017; 3(2):95-110. https://doi.org/10.1159/000462979 PMid:28560220

Hurley HJ. Axillary hyperhidrosis, apocrine bromhidrosis, hidradenitis suppurativa, and familial benign pemphigus: surgical approach. In: Roenigk RK, Roenigk HH, editors. Dermatologic Surgery. New York: Marcel Dekker, 1996: 623–645.

Hamzavi IH, Griffith JL, Riyaz F, Hessam S, Bechara FG. Laser and light-based treatment options for hidradenitis suppurativa. J Am Acad Dermatol. 2015; 73(5 Suppl 1):S78-81. https://doi.org/10.1016/j.jaad.2015.07.050 PMid:26470622

Sartorius K, Lapins J, Emtestam L, Jemec GB. Suggestions for uniform outcome variables when reporting treatment effects in hidradenitis suppurativa. Br J Dermatol. 2003; 149(1):211-3. https://doi.org/10.1046/j.1365-2133.2003.05390.x PMid:12890229

Finlay AY, Khan GK. Dermatology Life Quality Index (DLQI)--a simple practical measure for routine clinical use. Clin Exp Dermatol. 1994;19(3):210–6. https://doi.org/10.1111/j.1365-2230.1994.tb01167.x

Downs AMR. Smoothbeam TM laser treatment may help improve hidradenitis suppurativa but not Hailey-Hailey disease J Cosmet Laser Ther. 2004; 6(3):163–164. https://doi.org/10.1080/14764170410003002

Sehgal VN, Verma P, Sawant S, Paul M. Contemporary surgical treatment of hidradenitis suppurativa (HS) with a focus on the use of the diode hair laser in a case. Journal of Cosmetic and Laser Therapy. 2011; 13(4):180-90. https://doi.org/10.3109/14764172.2011.594066 PMid:21714587

Valladares-Narganes LM, Rodríguez-Prieto MA, Blanco-Suárez MD, Rodriguez-Lage C, García-Doval I. Treatment of hidradenitis suppurativa with intralesional photodynamic therapy using a laser diode attached to an optical cable: a promising new approach. Br J Dermatol. 2015; 172(4):1136-9. https://doi.org/10.1111/bjd.13385 PMid:25196140

Xu LY, Wright DR, Mahmoud BH, Ozog DM, Mehregan DA, Hamzavi IH. Histopathologic study of hidradenitis suppurativa following long-pulsed 1064-nmNd:YAG laser treatment. Arch Dermatol. 2011; 147(1):21-8. https://doi.org/10.1001/archdermatol.2010.245 PMid:20855672

John H, Manoloudakis N, Stephen Sinclair J. A systematic review of the use of lasers for the treatment of hidradenitis suppurativa. J Plast Reconstr Aesthet Surg. 2016; 69(10):1374-81. https://doi.org/10.1016/j.bjps.2016.05.029 PMid:27496291

Agut-Busquet E, Romaní J, Gilaberte Y, García-Malinis A, Ribera-Pibernat M, Luelmo J. Photodynamic therapy with intralesional methylene blue and a 635 nm light-emitting diode lamp in hidradenitis suppurativa: a retrospective follow-up study in 7 patients and a review of the literature. Photochem Photobiol Sci. 2016; 15(8):1020-8. https://doi.org/10.1039/C6PP00082G PMid:27417568

Zerbinati N, D'Este E, Ini L, Baruffato A, Premoli V, Calligaro A, Paulli M. Clinical and histological changes in Hidradenitis suppurativa following 1064 nm nd:YAG intralesional laser treatment. J Biol Regul Homeost Agents. 2017; 31(2 Suppl. 2):131-140. PMid:28702973

Published
2018-01-07
How to Cite
1.
Fabbrocini G, França K, Lotti T, Marasca C, Annunziata MC, Cacciapuoti S, Masar&Atilde; A, Romanelli M, Lotti J, Wollina U, Tchernev G, Zerbinati N. Intralesional Diode Laser 1064 nm for the Treatment of Hidradenitis Suppurativa: A Report of Twenty Patients. Open Access Maced J Med Sci [Internet]. 2018Jan.7 [cited 2021Mar.4];6(1):31-4. Available from: https://www.id-press.eu/mjms/article/view/oamjms.2018.045

Most read articles by the same author(s)

1 2 3 > >>