Report on von Willebrand Disease in Malaysia

  • Mercy Halleluyah Periayah Reconstructive Sciences Unit, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan
  • Ahmad Sukari Halim Reconstructive Sciences Unit, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan
  • Arman Zaharil Mat Saad Reconstructive Sciences Unit, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan
  • Nik Soriani Yaacob Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan
  • Faraizah Abdul Karim Hemophilia Clinic, National Blood Centre (Pusat Darah Negara), Jalan Tun Razak, 50400, Wilayah Persekutuan, Kuala Lumpur
Keywords: von Willebrand Disease, Malaysian report, Sociodemographic details, Laboratory profiles, Year 2011-2013

Abstract

BACKGROUND: Von Willebrand disease (vWD) is an inherited hemostatic disorder that affects the hemostasis pathway. The worldwide prevalence of vWD is estimated to be 1% of the general population but only 0.002% in Malaysia.

AIM: Our present paper has been written to disclose the statistical counts on the number of vWD cases reported from 2011 to 2013.

MATERIAL AND METHODS: This article is based on sociodemographic data, diagnoses and laboratory findings of vWD in Malaysia. A total of 92 patients were reported to have vWD in Malaysia from 2011 to 2013.

RESULTS: Sociodemographic-analysis revealed that 60% were females, 63% were of the Malay ethnicity, 41.3% were in the 19-44 year old age group and 15.2% were from Sabah, with the East region having the highest registered number of vWD cases. In Malaysia, most patients are predominately affected by vWD type 1 (77.2%). Factor 8, von Willebrand factor: Antigen and vWF: Collagen-Binding was the strongest determinants in the laboratory profiles of vWD.

CONCLUSION: This report has been done with great interest to provide an immense contribution from Malaysia, by revealing the statistical counts on vWD from 2011-2013.

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Published
2016-02-29
How to Cite
1.
Periayah MH, Halim AS, Mat Saad AZ, Yaacob NS, Karim FA. Report on von Willebrand Disease in Malaysia. Open Access Maced J Med Sci [Internet]. 2016Feb.29 [cited 2020Dec.5];4(1):112-7. Available from: https://www.id-press.eu/mjms/article/view/oamjms.2016.030
Section
B - Clinical Sciences