The Difference of Brainstem Auditory Evoked Potential Latency in Diabetic Patient with Good and Poor Glycemic Control

  • D. P. G. Purwa Samatra Department of Neurology, Faculty of Medicine, Udayana University and Sanglah General Hospital, Bali, Indonesia
  • Grace Meliana Department of Neurology, Faculty of Medicine, Udayana University and Sanglah General Hospital, Bali, Indonesia
  • I. G. N. Purna Putra Department of Neurology, Faculty of Medicine, Udayana University and Sanglah General Hospital, Bali, Indonesia
  • I Putu Eka Widyadharma Department of Neurology, Faculty of Medicine, Udayana University and Sanglah General Hospital, Bali, Indonesia
Keywords: Brainstem auditory evoked potential, Diabetes mellitus, Glycemic control

Abstract

BACKGROUND: Diabetes mellitus (DM) is a metabolic disorder which may complicate other organs, including the nervous system. Literatures which discuss about DM complications in the peripheral nervous system are easy to find but not so many of the central nervous system. Central diabetic neuropathy is a new concept which could be detected by a simple and non-invasive method, called brainstem auditory evoked potential (BAEP).

AIM: The aim of the study was to find differences in BAEP latencies of a diabetic patient with good and poor glycemic control.

METHODS: This was a cross-sectional study of 80 patients who came for follow-up in diabetic center and neurology polyclinic at Sanglah Hospital, from April to July 2016. The subjects were divided into two groups, depending on their glycemic control, then having BAEP examination.

RESULTS: The unpaired t-test found prolonged BAEP latencies (either peak latency of wave III, V, IPL I-III, III-V, and I-V) in both ears at the poor glycemic control group, but the results were not differed significantly (p > 0.05).

CONCLUSION: BAEP wave latencies were found prolonged in DM patient with poor glycemic control but not statistically significant. Further evaluation of BAEP latencies in DM patients is needed with prolonged duration and their relation with other comorbid factors, especially smoking habit.

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References

Agarwal N, Deshpande VK, Biswas DA, Babbar R. Auditory and neurological correlation in auditory and peripheral neuropathy in Type II diabetes mellitus. Int J Physiol. 2013;1(2):71-6. https:// doi.org/10.5958/j.2320-608x.1.2.015

Aslam A, Singh J, Rajbhandari S. Pathogenesis of painful diabetic neuropathy. Pain Res Treat. 2014;2014:1-7. https://doi. org/10.1155/2014/412041 PMid:24891949

Infodatin. Kementerian Kesehatan RI. Available from: http://www. depkes.go.id/download.php?file=download/puspadatin/infodatin/ infodatin-diabetes.pdf. [Last accessed on 2014 Mar 03].

Brainbridge KE, Cheng YJ, Cowie CC. Potential mediators of diabetes-related hearing impairment in the U.S population. Diabetes Care. 2010;33(4):811-6. https://doi.org/10.2337/ dc09-1193 PMid:20097782

Pemmaiah KD, Srinivas DR. Hearing loss in diabetes mellitus. Int J Collab Res Intern Med Public Health. 2011;3(10):724-31.

Konrad-Martin D, Austin DF, Griest S, McMillan GP, McDermot D, Fausti S. Diabetes-related changes in auditory brainstem responses. Laryngoscope. 2010;120(1):150-8. https://doi. org/10.1002/lary.20636 PMid:19904812

Vivek H, Nitin D, Sonali K, Priti D, Kanchan D, Ashish G. Hearing status in patients with diabetes mellitus. Panacea J Med Sci. 2012;2(1):25-8.

Takkar J, Manchanda KC, Bansal B, Gahlot S, Grover GS. Evaluation of auditory neuropathy in Type-2 diabetes mellitus using brainstem auditory evoked potentials. Int J Res Health Sci. 2013;1(2):74-9.

Abdulkadiroglu Z, Kaya A, Gonen S, Ilhan N. Brainstem auditory evoked potentials in patients with Type 2 diabetes mellitus. Turk J Endocrinol Metab. 1999;1:29-32.

Shatdal C, Prahlad K, Kumar BB, Sushila P. Evaluation of brainstem auditory evoked potential in diabetics. J Univ Coll Med Sci. 2013;1(2):8-12.

Siddiqi S, Gupta R, Aslam M, Hasan SA, Khan SA. Type-2 diabetes mellitus and auditory brainstem response. Indian J Endocrinol Metab. 2013;17(6):1073-7. https://doi. org/10.4103/2230-8210.122629 PMid:24381887

Gupta S, Baweja P, Mittal S, Kumar A, Singh KD, Sharma R. Brainstem auditory evoked potential abnormalities in Type 2 diabetes mellitus. North Am J Med Sci. 2013;5(1):60-5. https:// doi.org/10.4103/1947-2714.106211 PMid:23378959

Li XP, Li RY, Li M, Zhang YZ, Guo KS, Wu LP. Effects of diabetes on hearing and cochlear structures. J Otol. 2013;8(2):82-7.

Abo-Elfetoh NM, Mohamed ES, Tag LM, El-Baz MA, Elden MA. Auditory dysfunction in patients with Type 2 diabetes mellitus with poor versus good glycemic control. Egyp J Otolaryngol. 2015;31(3):162-9. https://doi.org/10.4103/1012-5574.161603

Dolu H, Ulas UH, Bolu E, Ozkardes A, Odabasi Z, Ozata M, et al. Evaluation of central neuropathy in Type II diabetes mellitus by multimodal evoked potentials. Acta Neurol Belg. 2003;103(4):206-11. PMid:15008505

Tóth F, Várkonyi TT, Rovó L, Lengyel C, Légrády P, Jóri J. Investigation of auditory brainstem function in diabetic patients. Int Tinnitus J. 2003;9(2):84-6. https://doi. org/10.1080/010503901300007380 PMid:15106279

León-Morales DL, Jáuregui-Renaud K, Garay-Sevilla ME, Hernández-Prado J, Malacara-Hernández JM. Auditory impairment in patients with Type 2 diabetes mellitus. Arch Med Res. 2005;36(5):507-10. https://doi.org/10.1016/j. arcmed.2005.02.002 PMid:16099330

Talebi M, Moosavi M, Mohamadzade NA, Mogadam R. Study on brainstem auditory evoked potentials in diabetes mellitus. Neurosciences (Riayadh). 2008;13(4):370-3. PMid:21063364

Dabrowski M. Disorders of hearing in diabetes mellitus. Diapedia 2014;8:7105378814. http://dx.doi.org/10.14496/ dia.7105378814.8

American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2013;36(1):S67-74. https:// doi.org/10.2337/dc13-s067 PMid:23264425

PB Perkeni. Konsensus Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 di Indonesia. Jakarta: PB Perkeni; 2015.

Huang CH, Lu CH, Chang HW, Tsai NW, Chang WN. Brainstem auditory evoked potentials study in patients with diabetes mellitus. Acta Neurol Taiwan. 2010;19(1):33-40. PMid:20714950

Vaughan N, James K. McDermot D, Fausti S. Auditory brainstem response difference in diabetic and non-diabetic veterans. J Am Audiol. 2007;18(10):863-71. https://doi.org/10.3766/ jaaa.18.10.5 PMid:18496995

Mahallik D, Sahu P, Mishra PR. Evaluation of auditory brain-stem evoked response in the middle: Aged Type 2 diabetes mellitus with normal hearing subjects. Indian J Otol. 2014;2(4):199-201. https://doi.org/10.4103/0971-7749.146939

Husten CG. How should we define light or intermittent smoking? Does it matter? Nicotine Tob Res. 2009;11(2):111-21. https://doi. org/10.1093/ntr/ntp010 PMid:19246425

Soepardi EA, Iskandar N, Bashiruddin J, Restuti RD. Buku Ajar Ilmu Kesehatan Telinga, Hidung, Tenggorok, Kepala Leher. Jakarta: Fakultas Kedokteran Universitas Indonesia; 2007. https://doi.org/10.26911/theijmed.2016.01.03.08

Gupta R, Aslam M, Hasan SA, Siddiqi SS. Type-2 diabetes mellitus and auditory brainstem responses-a hospital-based study. Indian J Endocrinol Metab. 2010;14(1):9-11. https://doi. org/10.4103/2230-8210.122629 PMid:21448408

Xie XT, Liu Q, Wu J, Wakui M. Impact of cigarette smoking in Type 2 diabetes development. Acta Pharmacol Sin. 2009;30(6):784- 7. https://doi.org/10.1038/aps.2009.49 PMid:19434055

Ash Factsheet. Smoking and Diabetes. 2015. Available from: http://www.ash.org.uk/files/document/ASH_128. [Last accessed on 2016 Jul 27].

Eliasson B. Worsening the blow: The effect of smoking on diabetes complication. Diabetes Voice. 2005;50:27-9.

Published
2020-04-20
How to Cite
1.
Samatra DPGP, Meliana G, Putra IGNP, Widyadharma IPE. The Difference of Brainstem Auditory Evoked Potential Latency in Diabetic Patient with Good and Poor Glycemic Control. Open Access Maced J Med Sci [Internet]. 2020Apr.20 [cited 2020Oct.29];8(B):457-62. Available from: https://www.id-press.eu/mjms/article/view/3403