Small Dysplastic Congenital Melanocytic Nevi in Childhood as Possible Melanoma Imitators
Small pigmented lesions in children can represent a significant diagnostic challenge. If the diagnostic features and therapeutic approach are relatively well established in large and giant nevi, there is still much controversy regarding small and intermediate-sized congenital pigmented lesions that can lead to significant diagnostic challenges, both clinically and dermoscopically, and consequently to difficulty in defining the optimal approach in such cases. Although dermoscopy can be useful in the diagnosis of pigmented lesions, the diversity of clinical and dermoscopic features of pigmented nevi in children usually hinder the differentiation between them and melanoma. Histological findings after resection often show surprising results that do not correspond either to the clinical nor the dermoscopic features. With the present case, we want to emphasise the variable natural behaviour of melanocytic lesions in children, which sometimes leads to unnecessary surgical excisions, which should be avoided in pediatric patients.
Plum Analytics Artifact Widget Block
Senthilkumar M, Thappa DM. Melanocytic nevi in children: A clinical study. Indian J Dermatol. 2006; 51:26-9. https://doi.org/10.4103/0019-5154.25184
Rogers T, Marino M, Raciti P, Jain M, Busam KJ, Marchetti MA, Marrghoob AA. Biologically distinct subsets of nevi G Ital Dermatol Venereol. 2016; 151(4): 365â€“384. PMid:27119653 PMCid:PMC5445663
Scope A, Dusza SW, Marghoob AA, Satagopan JM, Tavoloni G, Braga J, Psaty EL, Weinstock MA, Oliveria AS, Bishop M, Geller AC, Halpern AH. Clinical and dermoscopic stability and volatility of melanocytic nevi in a population-based cohort of children in Framingham school system. J Invest Dermatol. 2011; 131(8):1615â€“1621. https://doi.org/10.1038/jid.2011.107 PMid:21562569 PMCid:PMC3136658
Scope A, Marghoob AA, Dusza SW, Satagopan JM, Agero AL, Benvenuto-Andrade C, Lieb JA, Weinstock MA, Oliveria SA, Geller AC, Halpern AC. Dermoscopic patterns of naevi in fifth-grade children of the Framingham school system. Br J Dermatol. 2008; 158(5):1041-9. https://doi.org/10.1111/j.1365-2133.2008.08510.x PMid:18363751
Seidenari S, Pellacani G, Martella A, Giusti F, Argenziano G, Buccini P, Carli P, CatricalÃ C, De Giorgi V, Ferrari A, Ingordo V, Manganoni AM, Peris K, Piccolo D, Pizzichetta M. Instrument-, age- and site-dependent variations of dermoscopic patterns of congenital melanocytic naevi: a multicentre study. Br J Dermatol. 2006; 155(1):56-61. https://doi.org/10.1111/j.1365-2133.2006.07182.x PMid:16792752
Zalaudek I, Grinschgl S, Argenziano G, Marghoob AA, Blum A, Richtig E, Wolf IH, Fink-Puches R, Kerl H, Soyer HP, Hofmann-Wellenhof R. Age-related prevalence of dermoscopy patterns in acquired melanocytic naevi. Br J Dermatol. 2006; 154(2):299-304. https://doi.org/10.1111/j.1365-2133.2005.06973.x PMid:16433800
All rights reserved.