Kinetics of radioactive-labelled cortisol in rast
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Спироски (Spiroski), Мирко (Mirko), Јанкуловски (Jankulovski), Никола (Nikola), & Столевски (Stolevski), Владо (Vlado). (2016). Kinetics of radioactive-labelled cortisol in rast. Medicinska Misla, 27(1), 5–7. Retrieved from


Kinetics of tritium labeled coгtisol was performed in control rats, rats treated with Synacthen Depot and rats treated with Dexamethason i.m. Rats were injected with 2 microCuri directly into the lateral tail vein and timed samples were collected by aorta with heparin аѕ an anticoagulans.

The results have shown that treatment with Synacthen led to а smaller half - time and turn over time. Treatment with Dexamethason led to an increase of half-time and decrease of turnover tme.

lt could be concluded that change of the functional state of adrenal gland influence the kinetics of radioactive labeled cortisol.
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