TY - JOUR AU - Velkovski, Vilijam AU - Shabani, Ilir AU - Kamnar, Viktor AU - Gavrilovski, Antonio AU - Todorova, Teodora AU - Bogojevska-Doksevska, Milena AU - Popovska, Danica AU - Nikolikj-Dimitrova, Erieta PY - 2023/06/30 Y2 - 2024/03/28 TI - Avascular necrosis of the femoral head in patient with Lyme disease and Devic’s optic neuritis JF - Archives of Public Health JA - Arch Pub Health VL - 15 IS - 1 SE - Case Report DO - 10.3889/aph.2023.6078 UR - https://www.id-press.eu/aph/article/view/6078 SP - 126-133 AB - <p>Avascular necrosis of the femoral head is a condition that leads to the collapse of the femoral head, which eventually ends in osteonecrosis of the hip head and the need for a total hip replacement. It affects patients of both sexes between 20-55 years of age. The pathogenetic cause is a progressive reduction of blood circulation which leads to destruction of the femoral head. Most often the causes are corticosteroid therapy, alcoholism, smoking, trauma, etc. Decompression of the femoral head accompanied by application of mesenchymal stem cells to the necrotic zone is a promising regenerative method of treatment. We present a case of a 20-year-old patient who was diagnosed with avascular necrosis of the femoral head of the left hip, due to a high dosage of corticosteroid therapy, with Lyme disease and Devic’s optic neuritis. Corticosteroid- induced avascular necrosis of the femoral head most commonly affects the femoral head, but other skeletal parts are not excluded. Majority of patients complain of pain with an insidious onset, which exacerbates with physical activity, and tends to worse with time. Early diagnosis and treatment arecrucial. Despite some controversy regarding the treatment of avascular necrosis of the femoral head with stem cells, the general outcomes of using stem cells appear to be positive in terms of efficacy and safety.</p> ER -