The Correlation between Body Mass Index with the Occurrence of Skin Tag

Nelva K. Jusuf, Imam B. Putra, Johan Kartayana

Abstract


BACKGROUND: Skin tag is a benign tumour of the skin with a soft consistency which commonly occurs in the flexure area. Skin tag often found in individuals with middle and old age. Until now, there are many of theories have been proposed to explain the mechanism of the skin tag, one of the theory is obesity.

AIM: To determine the body mass index (BMI) in patients with skin tag.

METHODS: This study is an analytic study with cross-sectional designs involving 32 subjects with skin tag and 32 controls. Diagnosis of skin tag was made based on anamnesis and clinical examination. All subjects underwent a physical examination (height and weight) to determine BMI (weight in kilogrammes divided by the square of height in meters). To analyse association between higher BMI with the occurrence of skin tag we use student t-test.

RESULTS: The mean BMI in the skin tag group (28.1+ 3.9 kg/m^2) was higher compared with the control group (24.1 + 2.3 kg/m^2). Statistical analysis by Student t-test found the p-value < 0.05.

CONCLUSION: We found a correlation between increased BMI with the occurrence of the skin tag.

Keywords


Skin tag; obesity; BMI

Full Text:

PDF OnlineFirst

References


Ko CJ. Dermal Hypertrophies and Benign Fibroblastic/Myofibroblastic Tumors. In: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffel DJ, Wolff K, editors. Fitzpatrick's Dermatology in General Medicine. 8th ed. New York: McGraw Hill Companies, 2012:p.707-18.

Quinn AG, Perkins W. Non-Melanoma Skin Cancer and Other Epidermal Skin Tumours. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook's Textbook of Dermatology. 8th ed. Oxford: Wiley-Blackwell, 2010:p.2613-61. https://doi.org/10.1002/9781444317633.ch52

Tamega AA, Aranha AM, Guiotoku MM, Miot LD, Miot HA. Association between skin tags and insulin resistance. An Bras Dermatol. 2010;85(1):25-31. https://doi.org/10.1590/S0365-05962010000100003

Sudy E, Urbina F, Maliqueo M, Sir T. Screening of glucose/insulin metabolic alterations in men with mutiple skin tag on the neck. JDDG. 2008;6:852-5. PMid:18397315

Erkek E, Kasi U, Bagci Y, Sezikli H. Leptin resistance and genetic predisposition as potential mechanism in the development of Skin tag. Hong Kong J Dermatol Venerol. 2011;19:108-14.

Tosson Z, Ibrahim SA, Kandil AH, Husam M. Relationship between skin tags, leptin hormone and metabolic disturbances. Egypt Dermatology Online Journal. 2013;9(2):1-12.

Sudy E, Urbina F, Maliqueo M, Sir T. Screening of glucose/insulin metabolic alterations in men with mutiple skin tag on the neck. JDDG. 2008;6:852-5. PMid:18397315

El-Zawahary KM, Abdallah M, Elmahdy HE. Study of the possible relationship between skin tags and obesity in Egypt. The Egyptian Journal of Dermatology and Venereology. 2013;33(1):18-21.

Chairawaty T, Ginting O, Putra IB. Lipid profile and Body Mass Index in Skin Tag patient [thesis]. Medan: University of Sumatera Utara, 2014.

Barbato MT, Criado PR, Silva Ana KD, Averbeck E, Guerine MB, Sá NB. Association of acanthosis nigricans and skin tags with insulin resistance. An Bras Dermatol. 2012;87(1):97-104. https://doi.org/10.1590/S0365-05962012000100012 PMid:22481657

Idris S, Sunitha S. Assessment of BMI, Serum Leptin Levels and Lipid Profile in Patients with Skin Tags. Journal of Clinical and Diagnostic Research. 2014; 8(9):1-3.

World Health Organization. Appropriate body-mass index for Asian populations and implications for policy and intervention strategies. Lancet. 2004;363:157-63. https://doi.org/10.1016/S0140-6736(03)15268-3

Sari R, Akman A, Alposy E, Balci MK. The Metabolic profile in patients with skin tags. Clin Exp Med. 2010;10:193-7. https://doi.org/10.1007/s10238-009-0086-5 PMid:20033751

Demir S, Demir Y. Acrochordon and impaired carbohydrate metabolism. Acta Diabetol. 2002;39:57-9. https://doi.org/10.1007/s005920200014 PMid:12120914

Hegazy SK, El-Ashmawy NE. Leptin and c-reactive protein are implicated in pathogenesis of skin tag. Journal of Diabetes Research & Clinical Metabolism. 2013:2-5.

Rasi A, Soltani-Arabshashi R, Shahbazi N. Skin tag as a cutaneous marker for impaired carbohydrate metabolism: a case-control study. Int J dermatol. 2007;46(11):1155-9. https://doi.org/10.1111/j.1365-4632.2007.03287.x PMid:17988334

Agamia NF, Gomaa SH. Assessment of serum leptin, atherogenic lipids, glucose level, insulin resistance and metabolic syndrome in patients with skin tags. Egpyt J Dermatol Venerol. 2014;34:58-64. https://doi.org/10.4103/1110-6530.137314

Bosseila M, Shaker O. The Tissue Expression of Insulin-Like Growth Factor (IGF-1) in Acrochordons. J Egypt wom Dermatol Soc. 2007

Shahjee HM, Bhattacharyya N. Activation of various downstream signaling molecules by IGFBP-3. J Cancer Ther. 2014;5(9):830-5. https://doi.org/10.4236/jct.2014.59091

PMid:25254143 PMCid:PMC4170070

Jowkar F, Fallahi A, Namazi MR. Is there any relation between serum insulin and insulin-like growth factor-I in non-diabetic patients with skin tag? JEADV. 2010;24:73-4. https://doi.org/10.1111/j.1468-3083.2009.03268.x PMid:19453787

Gorpelioglu C, Erdal E, Ardicoglu Yetal. Serum leptin, atherogenic lipids and glucose levels in patients with skin tag. Indian J Dermatol. 2009;54(1):20-2. https://doi.org/10.4103/0019-5154.48980 PMid:20049263 PMCid:PMC2800864




DOI: http://dx.doi.org/10.3889/oamjms.2017.061

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM

Refbacks

  • There are currently no refbacks.




Copyright (c) 2017 Nelva K. Jusuf, Imam B. Putra, Johan Kartayana

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

 



Published by: Id Design 2012/DOOEL Skopje, Republic of Macedonia